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Pyrimidines

Pyrimidine is an organic compound with an aromatic and heterocyclic structure, closely resembling pyridine. It belongs to the class of diazines, which are heterocyclic compounds containing two nitrogen atoms in the six-membered ring. In pyrimidine, the nitrogen atoms are positioned at positions 1 and 3 within the ring.

The principal synthesis for the production of pyrimidines usually involves the cyclization of β-dicarbonyl compounds with N-C-N compounds. Typical reactions include the synthesis of 2-substituted pyrimidines by reacting the former with amidines, the synthesis of 2-pyrimidinones by reacting with urea, and the synthesis of 2-aminopyrimidines by reacting with guanidines.

Pyrimidines are typically utilized by cells as a source of energy, and they are crucial for synthesizing DNA and RNA, proteins, starch, regulating enzymes, signaling between cells, and other important biological functions.

Pyrimidines, also known as 1,3-diazines, consist of a six-membered heteroaromatic ring that contains two nitrogen atoms located at positions 1 and 3. This chemical compound is one of three isomeric forms of diazine, the other two being pyridazine and pyrazine.

Pyrimidines, similar to pyridines, exhibit a greater decrease in π-electron density. As a result, electrophilic aromatic substitution is hindered, while nucleophilic aromatic substitution is promoted.

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Catalog #
Compound Name
Structure
Z-09462

5-Pyrimidineacetic acid

Purity: 97%
5267-07-2
Z-09305

Ethyl 2-(methylthio)-6-oxo-1,6-dihydropyrimidine-5-carboxylate

Purity: 96%
53554-29-3
Z-09474

2,4,6-Trichloro-5-fluoropyrimidine

Purity: 98%
6693-08-9
Z-09307

2-(Chloromethyl)-5-methylpyrimidine

Purity: 95%
126504-85-6
Z-09501

2,4,6-Triaminopyrimidine

Purity: 97%
1004-38-2
Z-09308

Methyl 5-methylpyrimidine-2-carboxylate

Purity: 95%
76196-80-0
Z-09571

(S)-1-Methyl-2,6-dioxohexahydropyrimidine-4-carboxylic acid

Purity: 95%
103365-69-1
Z-09309

5-Chloro-2-methylpyrimidine

Purity: 98%
54198-89-9
Z-09715

2-Chloro-5-ethylpyrimidine

Purity: 95%
111196-81-7
Z-09364

2-Amino-4-oxo-1,4-dihydropyrimidine-5-carbonitrile

Purity: 95%
27058-50-0
Z-09747

2-Chloromethyl-4,6-dimethoxypyrimidine

Purity: 95%
114108-86-0
Z-09372

2-(Methylthio)pyrimidine-5-carbonitrile

Purity: 95%
38275-43-3
Z-09774

4,5-Dichloro-6-ethylpyrimidine

Purity: 95%
115617-41-9
Z-09379

4-Aminopyrimidine-5-carbonitrile

Purity: 97%
16357-69-0
Z-09895

2-Bromo-5-chloropyrimidine

Purity: 95%
124405-67-0
Z-09382

Methyl 2-oxo-1,2-dihydropyrimidine-5-carboxylate

Purity: 95%
50628-34-7
Z-10022

2-Methyl-4,6-dimethoxypyrimidine

Purity: 95%
13566-48-8
Z-08922

5-(Hydroxymethyl)pyrimidine

Purity: 95%
25193-95-7
Z-09276

Ethyl 2-chloropyrimidine-5-carboxylate

Purity: 95%
89793-12-4
Z-08939

Pyrazolo[1,5-a]pyrimidine-3-carbonitrile

Purity: 95%
25939-87-1
Z-09294

2,4-Dichloro-7-methylthieno[3,2-d]pyrimidine

Purity: 99%
35265-83-9
Z-09023

5-Bromopyrazolo[1,5-a]pyrimidine

Purity: 97%
1159981-95-9
Z-09024

Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Purity: 97%
25940-35-6
Z-08793

4-(Hydroxymethyl)pyrimidine

Purity: 98%
33581-98-5
Z-09122

2-Methyl-4,6-dichloropyrimidine

Purity: 97%
1780-26-3
Z-08798

2-(Chloromethyl)pyrimidine

Purity: 95%
54198-88-8
Z-09129

2-Chloro-5-fluoropyrimidine

Purity: 99%
62802-42-0
Z-08808

4-Chloro-2-methylthieno[2,3-d]pyrimidine

Purity: 95%
56843-79-9
Z-09159

5-Chloropyrimidine-2-carbonitrile

Purity: 95%
38275-56-8
Z-08872

7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol

Purity: 95%
39929-79-8
Z-09160

2,4-Dichloropyrimidine-5-carbonitrile

Purity: 95%
3177-24-0
Z-08883

3-Aminopyrazolo[1,5-a]pyrimidine

Purity: 95%
232600-93-0
Z-09171

Ethyl 2-amino-4-hydroxypyrimidine-5-carboxylate

Purity: 95%
15400-53-0
Z-08890

Methyl pyrimidine-4-carboxylate

Purity: 95%
2450-08-0
Z-09181

3-Bromo-7-chloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine

Purity: 95%
1260787-71-0
Z-08918

4-Chlorobenzofuro[3,2-d]pyrimidine

Purity: 99%
39876-88-5
Z-09249

5-Bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyrimidine

Purity: 95%
478258-81-0
Z-08725

Methyl 6-aminopyrimidine-4-carboxylate

Purity: 95%
77817-12-0
Z-08603

Dimethyl 2-(methylthio)pyrimidine-4,5-dicarboxylate

Purity: 95%
132973-51-4
Z-08733

5-Bromo-2-ethynylpyrimidine

Purity: 95%
1135283-08-7
Z-08604

2-(Methylthio)pyrimidine-4,5-dicarboxylic acid

Purity: 95%
149771-16-4
Z-08734

4,6-Dichloro-2-(methylthio)pyrimidine-5-carbonitrile

Purity: 95%
33097-13-1
Z-08605

2-(Methylthio)furo[3,4-d]pyrimidine-5,7-dione

Purity: 95%
241469-90-9
Z-08786

2-Amino-5-methoxypyrimidine

Purity: 95%
13418-77-4
Z-08659

4-Bromo-6-methylpyrimidine

Purity: 96%
69543-98-2
Z-08662

5-Bromo-2-chloro-4-methylpyrimidine

Purity: 96%
633328-95-7
Z-08574

4-Amino-5-chloropyrimidine-2-carbonitrile

Purity: 95%
1260863-79-3
Z-08664

2,5-Dichloro-4-methylpyrimidine

Purity: 95%
1192064-63-3
Z-08591

1H-Pyrazolo[3,4-d]pyrimidine

Purity: 95%
271-80-7
Z-08666

2,5-Dibromo-4-methylpyrimidine

Purity: 97%
171408-73-4
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